山东省济宁市太白湖新区荷花路133号 科研楼3楼
anngyh@126.com
教育和工作经历
2016.09-至今 济宁医学院精准医学研究院/山东大学齐鲁医学院硕士生导师
2013.09- 2016.07 东北林业大学/中国农业科学院联合培养取得博士学位
2010.08- 2013.08 中国农业科学院 科研助理/研究实习员
研究领域与方向
（1）线粒体质量控制在炎性疾病发生及治疗中的作用机制
（2）细胞外囊泡在产科疾病的诊断及治疗中的应用
（3）干细胞分化机制及在疾病中的应用
荣誉、奖励及主要社会兼职
1. 中国老年学会精准医疗分会会员
2. 第十届山东省大学生生物化学技能大赛优秀指导教师
基金资助
1.国家自然科学基金面上项目（2025.01-2028.12）
2.国家自然科学基金青年基金项目（2019.01-2021.12）
3.山东省自然科学基金博士基金项目（2017.08-2019.12）
4.山东省高校科研项目（2017.07-2020.06）
5.济宁医学院国家自然科学基金培育基金（2017.09-2021.09）
6.济宁医学院青年博士科研启动基金（2016.12-2021.12）
代表性论文
1. Gao Y, Mi N, Wu W, Zhao Y, Fan F, Liao W, Ming Y, Guan W*, Bai C*. Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis. J Extracell Vesicles. 2024 Feb;13(2):e12410.
2. Gao Y, Mi N, Zhang Y, Li X*, Guan W*, Bai C*. Uterine macrophages as treatment targets for therapy of premature rupture of membranes by modified ADSC-EVs through a circRNA/miRNA/NF-κB pathway. J Nanobiotechnology. 2022 Nov19;20(1):487.
3. Shao Y, Wu W, Fan F, Liu H, Ming Y, Liao W, Bai C*, Gao Y*. Extracellular Vesicle Content Changes Induced by Melatonin Promote Functional Recovery of Pancreatic Beta Cells in Acute Pancreatitis. J Inflamm Res. 2023 Dec 27;16:6397-6413.
4. Hao Y, Yang Q, Zhang H, Bai C,Liu X, Gao Y. Ginger-Derived Extracellular Vesicles: A Natural Solution for Alopecia,Current Drug Delivery,2023,8.
5. Bai C, Zhang H, Zhang X, Yang W, Li X*, Gao Y*. MiR-15/16 mediate crosstalk between the MAPK and Wnt/β-cateninpathways during hepatocyte differentiation from amniotic epithelial cells. BBA- Gene Regulatory Mechanisms. 2019,1862(5):567-581.
6. Gao Y, Ma L, Bai C*, Zhang X , Yang W. Melatonin promotesself-renewal and nestin expression in neural stem cells from the retina.
Histol Histopathol. 2019,34(6):645-654.
7. Gao Y, Zhang R, Dai S, Zhang X, Li X*, Bai C*. Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation. Front Cell Dev Biol. 2019,20(7):351.
8. Gao Y, Zhang R, Wei G, Dai S, Zhang X, Yang W, Li X*, Bai C*. Long Non-coding RNA Maternally Expressed 3 Increases the Expression of Neuron-Specific Genes by Targeting miR-128-3p in All-Trans Retinoic Acid-Induced Neurogenic Differentiation From Amniotic Epithelial Cells. Front Cell Dev Biol. 2019,23(7):342.
9. Gao Y, Bai C, Zheng D, Li C, Zhang W, Li m, Guan W*, Ma Y*. Combination of melatonin and Wnt-4 promotes neuralcell differentiation in bovine amniotic epithelial cells and recovery fromspinal cord injury. J Pineal Res.2016; 60:303-312 .
10. Gao Y, Li X, Zheng D, Guan W*, Ma Y*. Isolation of a Pluripotent Neural Stem Cell from the Embryonic Bovine Brain. Int. J. Mol. Sci. 2015, 16: 5990-5999.
11. Gao Y, Guan WJ*, Ma YH*. A Short Review: Research progress ofbovine stem cells. Cell Mol Biol (Noisy-le-grand). 2015,61(5),74-78.
12. Gao Y, Pu Y, Wang D, Hou L, Guan W*, Ma Y*. Isolation and Biological Characterization of Chicken Amnion Epithelial Cells, Eur J Histochem. 2012; volume 56:e33.
13. Gao Y, Bai C, Xiong H, Li Q, Shan Z, Huang L, Ma Y*, Guan W*. Isolation and Characterization of Chicken Dermis-Derived MesenchymalStem/Progenitor Cells,Biomed Res Int, 2013, 626258.