lil1987@126.com

教育和工作经历

2019.07-至今        济宁医学院精准医学研究院

2016.01- 2019.04   暨南大学 博士后

2010.09- 2015.12   山东农业大学 动物遗传育种与繁殖专业博士

2008.09- 2010.07   临沂师范学院 生物科学 学士

研究领域与方向

主要研究：肿瘤细胞代谢异常的分子机制及功能研究

基金资助

1. 国家自然科学基金青年基金项目：葡萄糖饥饿条件下AMPK-HDAC4-HSP90β1信号通路促进结肠癌细胞增殖的分子机制研究（2021.01-2023.12）

2. 济宁医学院博士科研启动基金（2019.07-2024.9）

3. 济宁医学院国基金培育基金（2020.01-2022.12）

代表性论文

1. Li Y, Wang S, Zhang X, Yang R, Wei X, Yan R, Jiang Y, Shen W. Expression Characteristics and Significant Prognostic Values of PGK1 in Breast Cancer. Front Mol Biosci. 2021 Jul 5;8:695420.

2. Li Y^#, Liang R^#, Sun M^#, Li Z, Sheng H, Wang J, Xu P, Liu S, Yang W, Lu B, Zhang S^*, Shan C^*.AMPK-dependent phosphorylation of HDAC8 triggers PGM1 expression to promote lung cancer cell survival under glucose starvation.Cancer Lett. 2020 May 28;478:82-92. 

3. Li Y^#, Liang R^#, Zhang X, Wang J, Shan C^*, Liu S^*, Li L^*, Zhang S^*. Copper Chaperone for Superoxide Dismutase Promotes Breast Cancer Cell Proliferation and Migration via ROS-Mediated MAPK/ERK Signaling. Front Pharmacol. 2019 Apr 5;10:356.

4. Li Y^#, Liu H^#, Wang P, Wang L, Sun Y, Liu G, Zhang P, Kang L, Jiang S, Jiang Y^*.RNA-Seq Analysis Reveals Genes Underlying Different Disease Responses to Porcine Circovirus Type 2 in Pigs.PLoS One. 2016 May 12;11(5):e0155502. 

5. Li Y, Liang S, Liu H, Sun Y, Kang L, Jiang Y^*.Identification of a short interspersed repetitive element insertion polymorphism in the porcine MX1 promoter associated with resistance to porcine reproductive and respiratory syndrome virus infection. AnimGenet. 2015 Aug; 46 (4): 437-40.

6. Li Y^#, Sun Y^#, Xing F, Kang L, Wang P, Wang L, Liu H, Li Y, Jiang Y^*. Identification of a single nucleotide promoter polymorphism regulating the transcription of ubiquitin specific protease 18 gene related to the resistance to porcine reproductive and respiratory syndrome virus infection. Vet Immunol Immunopathol. 2014 Dec 15;162(3-4):65-71.